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Gavi pledges $1 billion for vaccine production in Africa; The latest health stories from around the world

Gavi, the Vaccine Alliance, has committed up to $1 billion to bolster Africa’s ability to sustainably produce its own doses of lifesaving vaccines. Manufacturers based in Africa produce only 1% of the vaccine doses used on the continent. https://www.science.org/content/article/news-glance-ai-rules-europe-vaccines-africa-and-union-nih-early-career-researchers?   Last week, Gavi announced that with money left over from the COVID-19 Vaccines Global Access Facility—an …

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UK approves CRISPR gene therapy for SCD; The latest health stories from around the world

In a world first, U.K. regulators have approved a therapy that uses CRISPR, the Nobel Prize–winning gene-editing tool invented in 2012. The treatment has been shown to help people with beta thalassemia and sickle cell disease, both inherited blood disorders that involve defects in the oxygen-carrying protein haemoglobin. It relies on removing blood stem cells …

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Genetic editing, the answer to bad cholesterol? The latest health stories from around the world

A technique for precisely rewriting the genetic code directly in the body has slashed “bad” cholesterol levels—possibly for life—in three people prone to dangerously high levels of the artery-clogging fat. The feat relied on a blood infusion of a so-called base editor, designed to disable a liver protein, PCSK9, that regulates cholesterol. https://www.science.org/content/article/base-editing-a-new-form-of-gene-therapy-sharply-lowers-bad-cholesterol?  “It is …

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USAID slashes funding for scheme identifying zoonotic diseases; The latest health stories from around the world

The U.S. Agency for International Development (USAID) has prematurely ended a $125 million program aimed at identifying viruses that might harm humans in animals. Many see this as a fallout from the concern that researchers studying bat viruses may have triggered the COVID-19 pandemic. https://www.science.org/content/article/u-s-cancels-program-aimed-identifying-potential-pandemic-viruses? USAID launched the program, known as the Discovery & Exploration …

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