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Two COVID-19 antibody therapies are no longer recommended by the WHO

Two COVID-19 antibody therapies are no longer recommended by the World Health Organization (WHO), on the basis that Omicron and the variant’s latest offshoots have likely rendered them obsolete. www.reuters.com/business/healthcare-pharmaceuticals/who-strongly-advises-against-use-two-covid-treatments-2022-09-15/? The two therapies – which are designed to work by binding to the spike protein of SARS-CoV-2 to neutralise the virus’ ability to infect cells …

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Historical precedents for poxvirus mutation

A few years ago, researchers scoured the remains of 1867 people who lived between 30,000 and 150 years ago for genetic traces of variola, the virus that causes smallpox. In the teeth and bones of four Northern Europeans from the Viking era, they found enough DNA to reconstruct entire variola genomes. The sequenced viruses weren’t …

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COVID-19 deaths lowest recorded since March 2020

  World Health Organization (WHO) Director General Tedros Adhanom Ghebreyesus has said: “Last week, the number of weekly reported deaths from COVID-19 was the lowest since March 2020. We have never been in a better position to end the pandemic.” But the WHO chief also warned that if the world does not seize the opportunity …

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Yet another COVID variant – Omicron BA.4.6

Another new COVID variant is spreading – here’s what we know about omicron BA.4.6 BA.4.6, a subvariant of the omicron COVID variant which has been quickly gaining traction in the US, is now confirmed to be spreading in the UK. The latest briefing document on COVID variants from the UK Health Security Agency (UKHSA) noted …

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Polio outbreak leads to state of emergency in New York

New York Governor Kathy Hochul  declared a state of emergency on Friday over a growing polio outbreak, in an effort to better equip health care providers with tools to curb the spread of the sometimes disabling virus before it takes further hold in the state. www.nytimes.com/2022/09/09/nyregion/new-york-polio-state-of-emergency.html? The order allows emergency service workers, midwives and pharmacists to …

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Philanthropist steps into the pharmaceutical field

Inspired by the record-fast creation of messenger RNA vaccines that blunted COVID-19’s impact, a philanthropist is providing AU$250 million ($172 million) over 20 years to bring similar alacrity to the development of therapeutics during future pandemic threats. Geoffrey Cumming, who made a fortune in oil and gas, is putting up what is believed to be …

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China enforces more lockdowns as cases of COVID-19 rise

China has restricted domestic travel as COVID outbreaks grow. China is stepping up its COVID defences as a key Communist Party meeting looms, restricting internal travel further as swathes of the country remain under tight lockdowns. The National Health Commission on Thursday announced a raft of measures that will be in place until the end …

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China locks down Chengdu following latest COVID-19 outbreak

China has locked down Chengdu, one of its biggest and most economically important cities, as it turns once again to its COVID strategy of restricting people’s movements to stop outbreaks. www.nytimes.com/2022/09/01/world/asia/china-covid-lockdown-chengdu.html Starting at 6 p.m. last Thursday, residents in the city of more than 21 million were no longer allowed to leave their homes without …

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Updated COVID-19 boosters get FDA emergency use authorisation; The latest health stories from around the world

The U.S. Food and Drug Administration (FDA) has granted an emergency use authorization for Moderna’s and Pfizer-BioNTech’s updated booster vaccines, which target the BA.4/BA.5 coronavirus subvariants. www.science.org/content/article/omicron-booster-shots-are-coming-lots-questions? For the first time since the start of the pandemic, COVID-19 vaccines look set to receive an update. Boosters reformulated to protect against the Omicron variant, which has …

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FDA approves another rare blood disorder treatment, sickle cell treatment on its way

The U.S. Food and Drug Administration last week approved a genetic treatment for the blood disorder beta-thalassemia, marking the third U.S. gene therapy for a rare disease. www.science.org/content/article/news-glance-new-gene-therapy-europe-s-drought-and-black-hole-s-photon-ring? The disorder causes low haemoglobin and severe anaemia, and the regular blood transfusions used to treat it can cause iron build-up that damages organs. The new treatment, …

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